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Dr. ir. Pieter C. Wuytens  (Postdoctoral Researcher)

This person worked in the group from 2012 till 2018.

Affiliation: IMEC
E-mail: [email protected]
Research Area: Photonic biosensor design and packaging
Promotor: Roel Baets
PhD Thesis: Pieter Wuytens, Oppervlakteversterkte Ramanspectroscopie voor intracellulaire metingen en de detectie van protease-activiteit: van chiptechnologie tot toepassingen, Surface-Enhanced Raman Spectroscopy for Intracellular Sensing and Protease Activity Detection: From Chip Technology to Applications, 10/2017
PieterWuytens
Pieter Wuytens graduated in 2012 as an Engineer (MsC)in Photonics from Vrije Universiteit Brussel, Belgium. In 2017 he obtained a PhD in Photonics Engineering and Applied Biological Sciences: Cell and Gene Technology at Ghent University. Since September 2017, he is active in the design and packaging of photonic integrated circuits for biosensing applications.

Specific Research Topics

Patents

Publications (43)

    International Journals

  1. N. Turk, A. Raza, P.C. Wuytens, H. Demol, M. van Daele, C. Detavernier, A. Skirtach, K. Gevaert, R. Baets, Waveguide-based surface-enhanced Raman spectroscopy detection of protease activity using non-natural aromatic amino acids , Biomedical Optics Express, 11(8), p.4800-4816 doi:10.1364/BOE.398038 (2020)  Download this Publication (1.2MB).
  2. N. Turk, A. Raza, P.C. Wuytens, M. Van Daele, C. Detavernier, A. Skirtach, K. Gevaert, R. Baets, Comparison of Free-Space and Waveguide-Based SERS Platforms., Nanomaterials (invited), 9(10), p.paper 1404 (1-14) doi:10.3390/nano9101401 (2019)  Download this Publication (1.8MB).
  3. A. Raza, S. Clemmen, P.C. Wuytens, M. de Goede, A. Tong, N. Le Thomas, C. Liu, J. Suntivich, A. Skirtach, S. Garcia-Blanco, D. Blumenthal, J. Wilkinson, R. Baets, High index contrast photonic platforms for on-chip Raman spectroscopy, Optics Express, 27(16), p.23067-23079 doi:10.1364/OE.27.023067 (2019)  Download this Publication (1.3MB).
  4. A. Raza, S. Clemmen, P.C. Wuytens, M. Muneeb, M. V. Daele, J. Dendooven, C. Detavernier, A. Skirtach, R. Baets, ALD assisted nanoplasmonic slot waveguide for on-chip Enhanced Raman Spectroscopy, Applied Physics Letters - Photonics, 3(11), p.116105 (12 pages) doi:10.1063/1.5048266 (2018)  Download this Publication (1.2MB).
  5. F. Peyskens, P.C. Wuytens, A. Raza, P. Van Dorpe, R. Baets, Waveguide excitation and collection of surface-enhanced Raman scattering from a single plasmonic antenna, Nanophotonics, 7(7), p.1299–1306 doi:10.1515/nanoph-2018-0003 (2018)  Download this Publication (1.1MB).
  6. P.C. Wuytens, H. Demol, N. Turk, K. Gevaert, A.G. Skirtach, M. Lamkanfi, R. Baets, Gold Nanodome SERS platform for label-free detection of protease activity, Faraday Discussions, 205(345), United Kingdom, p.345-361 doi:10.1039/c7fd00124j (2017)  Download this Publication (1.6MB).
  7. E. Lengert, M. Saveleva, A. Vsevolod, P.C. Wuytens, R. Kamyshinsky, A. Vasiliev, D. Gorin, G. Sukhorukov, A. G. Skirtach, B. Parakhonskiy, Silver alginate hydrogel micro- and nano- containers for theranostics: synthesis, encapsulation, remote release and detection, ACS Applied Materials & Interfaces, 2017(9), p.21949-21958 doi:10.1021/acsami.7b08147 (2017)  Download this Publication (6.8MB).
  8. P.C. Wuytens, A.G. Skirtach, R. Baets, On-Chip Surface-Enhanced Raman Spectroscopy using Nanosphere-Lithography Patterned Antennas on Silicon Nitride Waveguides, Optics Express, 25(11), p.12926-12934 doi:10.1364/oe.25.012926 (2017)  Download this Publication (6.3MB).
  9. A. Dhakal, P.C. Wuytens, A. Raza, N. Le Thomas, R. Baets, Silicon Nitride Background in Nanophotonic Waveguide Enhanced Raman Spectroscopy, Materials, 10(140), doi:10.3390/ma10020140 (2017)  Download this Publication (1.6MB).
  10. A. Dhakal, P.C. Wuytens, F. Peyskens, K. Jans, N. Le Thomas, R. Baets, Nanophotonic waveguide enhanced Raman spectroscopy of biological submonolayers, ACS Photonics, 3(12), p.2141-2149 doi:10.1021/acsphotonics.6b00593 (2016).
  11. A. Dhakal, F. Peyskens, S. Clemmen, A. Raza, P.C. Wuytens, H. Zhao, N. Le Thomas, R. Baets, Single mode waveguide platform for spontaneous and surface-enhanced on-chip Raman spectroscopy, Interface Focus (invited), 6(4), United Kingdom, p.article 20160015 doi:10.1098/rsfs.2016.0015 (2016).
  12. P.C. Wuytens, A. Subramanian, W. H. De Vos, A. G Skirtach, R. Baets, Gold nanodome-patterned microchips for intracellular surface-enhanced Raman spectroscopy, Analyst, 140(24), p.8080-8087 doi:10.1039/c5an01782c (2015)  Download this Publication (5.7MB).
  13. B.E. Pinchasik , J. Steinkuehler, P.C. Wuytens, A. G Skirtach, P. Fratzl, H. Möhwald, From Beetles in Nature to the Lab: Actuating Underwater Locomotion on Hydrophobic Surfaces, Langmuir, 31(51), p.13734–13742 doi:10.1021/acs.langmuir.5b03821 (2015)  Download this Publication (4.8MB).
  14. A. Subramanian, E.M.P. Ryckeboer, A. Dhakal, F. Peyskens, A. Malik, B. Kuyken, H. Zhao, S. Pathak, A. Ruocco, A. De Groote, P.C. Wuytens, D. Martens, F. Leo, W. Xie, U.D. Dave, M. Muneeb, Pol Van Dorpe, J. Van Campenhout, W. Bogaerts, P. Bienstman, N. Le Thomas, D. Van Thourhout, Zeger Hens, G. Roelkens, R. Baets, Silicon and silicon nitride photonic circuits for spectroscopic sensing on-a-chip , Photonics Research (invited), 5(3), p.B47 doi:10.1364/PRJ.3.000B47 (2015)  Download this Publication (1.5MB).
  15. P.C. Wuytens, B. Parakhonskiy, A. Yashchenok, M. Winterhalter, A. Skirtach, Pharmacological aspects of release from microcapsules—from polymeric multilayers to lipid membranes, Current Opinion in Pharmacology, 18, p.129-140 doi:10.1016/j.coph.2014.09.016 (2014)  Download this Publication (1.6MB).
  16. A. Dhakal, A. Subramanian, P.C. Wuytens, F. Peyskens, N. Le Thomas, R. Baets, Evanescent excitation and collection of spontaneous Raman spectra using silicon nitride nanophotonic waveguides, Optics Letters, 39(13), p.4025-4028 doi:10.1364/ol.39.004025 (2014).
      International Conferences

    1. N. Turk, A. Raza, P.C. Wuytens, H. Demol, M. van Daele, C. Detavernier, A. Skirtach, K. Gevaert, R. Baets, Waveguide-based Detection of Protease Activity using Surface-Enhanced Raman Spectroscopy, Frontiers in Optics, United States, (2020).
    2. N. Turk, A. Raza, P.C. Wuytens, H. Demol, A. Skirtach, K. Gevaert, R. Baets, Towards SERS-based on-chip detection of protease activity using nanoplasmonic slot waveguides, Proceedings of the 23rd Annual Symposium of the IEEE Photonics Benelux Chapter, Belgium, (2018).
    3. A. Raza, S. Clemmen, M. V. Daele, P.C. Wuytens, J. Dendooven, C. Detavernier, R. Baets, The comparison of on-chip SERS substrates: Nanoplasmonic bowtie antenna vs metal slot waveguide, Proceedings of the 23rd Annual Symposium of the IEEE Photonics Benelux Chapter, Belgium, (2018)  Download this Publication (408KB).
    4. A. Raza, M. Van Daele, P.C. Wuytens, J. Dendooven, C. Detavernier, S. Clemmen, R. Baets, E-beam-lithography free plasmonic slot waveguides for on-chip Raman spectroscopy, CLEO 2018, United States, p.paper SW3L.6 doi:10.1364/CLEO_SI.2018.SW3L.6 (2018).
    5. N. Turk, P.C. Wuytens, H. Demol, K. Gevaert, A. Skirtach, M. Lamkanfi, R. Baets, Towards multiplexed SERS-based on-chip detection of protease activity, International Conference on Biomedical Photonics, France, (2018).
    6. N. Turk, P.C. Wuytens, A. Raza, A. Skirtach, R. Baets, Organic Adhesion Layer for an Increased Waveguide-Excited Surface-Enhanced Raman Signal, Frontiers in Optics, United States, p.paper JW3A.82 (2 pages) doi:10.1364/fio.2017.jw3a.82 (2017)  Download this Publication (615KB).
    7. A. Raza, F. Peyskens, P.C. Wuytens, S. Clemmen, P. V. Dorpe, R. Baets, Detection of Surface-enhanced Raman Signals from a Single Nanoplasmonic Antenna Integrated on a Single Mode Waveguide , CLEO: Science and Innovations,, United States, p.paper SM.4D.6 doi:10.1364/cleo_si.2017.sm4d.6 (2017)  Download this Publication (559KB).
    8. P.C. Wuytens, A.G. Skirtach, R. Baets, Nanotriangle Decorated Silicon Nitride Waveguides for Integrated Surface-Enhanced Raman Spectroscopy, CLEO: Science and Innovations 2017, STh1M(8), United States, doi:10.1364/cleo_si.2017.sth1m.8 (2017)  Download this Publication (392KB).
    9. A. Raza, P.C. Wuytens, F. Peyskens, S. Clemmen, P. V. Dorpe, R. Baets, On-chip Enhanced Raman spectroscopy using metal slot waveguide, European Conference on Integrated Optics (ECIO), 19(T7.4), Netherlands, (2017).
    10. S. Clemmen, A. Raza, A. Dhakal, F. Peyskens, A. Subramanian, P, Van Dorpe, P.C. Wuytens, H. Zhao, E.M.P. Ryckeboer, S. Severi, N. Le Thomas, R. Baets, Spectroscopic sensing with silicon nitride photonic integrated circuits, Photonics West 2017, Proc. SPIE 10106, Integrated Optics: Devices, Materials, and Technologies XXI (invited), United States, p.101060T doi:10.1117/12.2256526 (2017)  Download this Publication (1.6MB).
    11. A. Dhakal, P.C. Wuytens, F. Peyskens, A. Skirtach, N. Le Thomas, R. Baets, Microscope-less Lab-on-a-chip Raman Spectroscopy of Cell-membranes, Photonics Conference (IPC2016), United States, p.144-145 doi:10.1109/ipcon.2016.7831017 (2016)  Download this Publication (236KB).
    12. A. Dhakal, A. Raza, P.C. Wuytens, F. Peyskens, A. Skirtach, R. Baets, Lab-on-a-chip Raman sensors outperforming Raman microscopes, CLEO, United States, p.paper SM2O.3 doi:10.1364/cleo_si.2016.sm2o.3 (2016).
    13. A. Dhakal, P.C. Wuytens, F. Peyskens, A. Subramanian, A. Skirtach, N. Le Thomas, R. Baets, Nanophotonic Lab-On-A-Chip Raman Sensors: a Sensitivity Comparison with Confocal Raman Microscope, BioPhotonics 2015, Italy, p.Th6.3 doi:10.1109/biophotonics.2015.7304021 (2015)  Download this Publication (433KB).
    14. S. Clemmen, H. Zhao, F. Peyskens, A. Dhakal, P.C. Wuytens, A. Subramanian, N. Le Thomas, R. Baets, Coherent anti-Stokes Raman spectroscopy on chip, 28th IEEE Photonics Conference (IPC 2015), United States, p.623-624 doi:10.1016/b978-0-12-710404-1.50007-3 (2015)  Download this Publication (169KB).
    15. P.C. Wuytens, W.H. Vos, A. Skirtach, R. Baets, Nanodome coins for intracellular surface-enhanced Raman spectroscopy, 3rd International Conference on BioPhotonics, Italy, p.paper P1.30 doi:10.1109/biophotonics.2015.7304044 (2015)  Download this Publication (552KB).
    16. R. Baets, A. Subramanian, A. Dhakal, F. Peyskens, P.C. Wuytens, E.M.P. Ryckeboer, G. Roelkens, N. Le Thomas, Spectroscopic sensing enabled by silicon photonics, Asia Communications and Photonics Conference (ACP) (invited), China, (2014)  Download this Publication (678KB).
    17. P.C. Wuytens, A. M. Yashchenok, A. Subramanian, A. G. Skirtach, R. Baets, Micron - sized dielectric chips with gold nanostructures for intracellular label - free SERS, 19 th Annual Symposium of the IEEE Photonics Society Benelux Chapter, (2014)  Download this Publication (1.9MB).
    18. R. Baets, A. Dhakal, F. Peyskens, P.C. Wuytens, A. Skirtach, N. Le Thomas, A. Subramanian, Resonant enhancement mechanisms in lab-on-chip raman spectroscopy on a silicon nitride waveguide platform, IEEE Photonics Conference 2014 (IPC) (invited), United States, p.500-501 doi:10.1109/ipcon.2014.6995468 (2014)  Download this Publication (1.2MB).
    19. A. Dhakal, P.C. Wuytens, F. Peyskens, A. Subramanian, N. Le Thomas, R. Baets, Evnascent Raman spectroscopy using photonic waveguides, International Conference on raman Spectroscopy- ICORS 2014, Germany, p.WeA-O-006 (2014)  Download this Publication (269KB).
    20. P.C. Wuytens, A. M. Yashchenok, A. Subramanian, R. Baets, A. G. Skirtach, Label-free monitoring of microcapsule-enabled intracellular release using gold-nanoparticle coated microchips , International Conference on Raman Spectroscopy, Germany, p.Mop-HS4-1 (2014).
    21. P.C. Wuytens, A. M. Yashchenok, A. Subramanian, R. Baets, A.G. Skirtach, Label-free monitoring of microcapsule-enabled intracellular release using goldnanoparticle coated microchips, Surface Enhanced Spectroscopies 2014, Germany, p.158 (2014)  Download this Publication (1.4MB).
    22. F. Peyskens, A. Subramanian, P. Neutens, A. Dhakal, P.C. Wuytens, P. Van Dorpe, N. Le Thomas, R. Baets, Enhancement of Raman scattering efficiency by on-chip nanoplasmonic antennas, Surface-Enhanced Spectroscopies 2014 conference, Germany, (2014).
    23. A. Dhakal, P.C. Wuytens, F. Peyskens, A. Subramanian, N. Le Thomas, R. Baets, Silicon-nitride waveguides for on-chip Raman spectroscopy, SPIE Photonics Europe 14, doi:10.1117/12.2057509 (2014)  Download this Publication (567KB).
    24. P.CU Wuytens, A. M. Yashchenok, A. Subramanian, A. G. Skirtach, R. Baets, Gold Nanoparticle Coated Silicon Nitride chips for Intracellular Surface-Enhanced Raman Spectroscopy, CLEO, STh4H.7, United States, doi:10.1364/cleo_si.2014.sth4h.7 (2014)  Download this Publication (217KB).
    25. A. Dhakal, P.C. Wuytens, F. Peyskens, A. Subramanian, N. Le Thomas, R. Baets, Raman spectroscopy using photonic waveguides, IPS Benelux 2013, Netherlands, (2013)  Download this Publication (5.5MB).
      National Journals

    1. B. Geers, B. Kuyken, P.C. Wuytens, R. Van Laer, T. Van Vaerenbergh, Laat er licht zijn: Fotonica, Eos magazine, 32(9), p.82-85 (2014).
      National Conferences

    1. P.C. Wuytens, A. Raza, H. Zhao, N. Turk, F. Peyskens, X. Nie, A. Dhakal, E.M.P. Ryckeboer, S. Clemmen, N. Le Thomas, R. Baets, On-chip Raman Spectroscopy, FEA Research Syposium 2017, Belgium, (2017)  Download this Publication (5MB).
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