Authors:	K. De Vos, J. Girones, T. Claes, E. Schacht, R. Baets, P. Bienstman
Title:	High throughput label-free biosensing with silicon-on-insulator microring resonators
Format:	International Conference Proceedings
Publication date:	3/2010
Journal/Conference/Book:	Europt(r)ode X
Location:	Czech Republic
Citations:	Look up on Google Scholar
Download:	(108KB)

Abstract

We have demonstrated simultaneous detection of multiple antibodies in a highly specific way. We discuss important considerations for high throughput sensing with silicon-on-insulator photonics, including detection limit, non-aggressive microfluidics packaging, receptor binding through a thin PEG layer, and camera based parallel readout. We introduce simultaneous measurement of refractive index and thickness of thin molecular layers, used to study conformational biomolecular changes.

Related Research Topics

• Optical label-free biosensors based on ring resonators

Related Projects

• GOA: UGent GOA biosensor project